Cancer - A Comprehensive Review

Abstract
Definition of Cancer
The Placement of Cancer in Causes of Death
Deaths by Type of Cancer
History of Cancer Stem Cells
Cancer Stem Cell
CSC Formation
How Do Cancer Stem Cells Occur?
EMT
Matrix Metalloproteinases
Metalloproteinase tissue inhibitors (TIMP)
Microenvironment
1. Inflammatory Environment
2. Hypoxic Environment (Lack of Oxygen)
3. Acidosis (Acidic Environment)
4. Exosomes
Metastasis, Invasion and Angiogenesis
Angiogenesis
Invasion
Current Cancer Treatments
Radiotherapy
Chemotherapy
Stem Cell Therapy
Hormonal Treatments
Surgical Methods
Biological Treatments: Immunotherapy, Cancer
Vaccines, Cancer Growth Inhibitors, Gene Therapy
Adoptive Immunotherapy
Immune System Supportive Treatments
Cytokines
Antibody Treatments
Monoclonal Antibodies (mAb) and Their
Mechanism of Action
Cetuximab and Panitumumab
Trastuzumab (Herceptin)
Rituximab and Similar
Alemtuzumab
Bevacizumab
Cancer Vaccines
Cancer Growth Inhibitors
Gene Therapy
Other Treatment Methods
References